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The advantage of this drug is that it does not target the isoform B of the IR which is involved in glucose metabolism and therefore does not induce the hyperglycaemia and metabolic toxicity observed with IGF-1R targeted therapies or TKIs ( In vitro and patient-derived xenograft (PDX) models of prostate cancer have since found evidence that PTEN and the abnormally spliced ligand independent androgen receptor variant 7 (AR-V7) could have potential use as biomarkers for response to this combination of therapy
No side effects and feeling great
Investigated for significant enhancement of cognitive function and memory in models of Alzheimer's and neurodegeneration
It is studied for its remarkable ability to promote tissue repair
Drugs 39 , 12841297 (2021)
